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When you're conducting research, you're not just looking at isolated mechanisms

thaliana ortholog of thiamine thiazole synthase (THI1) (Fig

Hernndez Borrero LJ, El-Deiry WS (2021) Tumor suppressor p53: biology, signaling pathways, and therapeutic targeting

In addition, this uncontrolled immune response could be potentiated by impaired pituitary function due to autoimmune damage, which manifests in symptoms varying in severity, such as fatigue, orthostatic hypotension and sleep disturbances, depending on the degree of pituitary damage (42, 59)