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In Group 4, there was a significant difference between the percentage of beta and glucagon cells with moderate GPX1 staining intensity ( p = 0.005)

Glyoxylate and dicarboxylate metabolism is closely linked to TCA cycle and photorespiration

DiAntonio A

Therefore, it is essential to thoroughly validate mouse findings in humanized models, like patient-derived iPSC 3D brain organoids, to ensure they are applicable to humans