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from Washington University School of Medicine provided normally aging C57BL/6 mice with NMN intervention therapy for up to 12 months

To identify pathways that were altered by vB12 treatment, we performed a pathway analysis (using a DAVID functional annotation tool) of up-regulated and down-regulated genes separately for each of the three categories of DEGs

Studies have shown a 77% reduction in pain, 78% improvement in mobility and 74% reduced consumption of analgesics with use of hyaluronic acid and chondroitin sulfate in osteoarthritis (118)

2021-2022 data were analyzed

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