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Nanoparticulate ophthalmic drug delivery of norfloxacin to prevent ocular infection after cataract surgery: evaluation in animal model

Clinical trials of the coadministered regimen (CagriSema) show greater bodyweight reduction than either agent alone [2]

& Gobbi, G

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36,37 Regarding molecular mechanisms underlying macrophage polarization, we found both p-JNK and p-NF-B to be notably increased in LPS-stimulated RAW264.7 cells but decreased after the hUC-MSCs treatment, suggesting that hUC-MSCs suppress LPS-induced macrophage M1 polarization by inhibiting JNK and NF-B activation