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Scoliosis in neurofibromatosis type 1 on whole-body magnetic resonance imaging:Frequency and association with intraspinal and paraspinal tumors

23 Indeed, directly targeting Ras using, among other agents, the farnesyltransferase inhibitor tipifarnib has been extremely challenging in general 24 and was also demonstrated to be ineffective in the treatment of pNF 25 (NCT00021541)

12, 16, 18 A high degree of synergistic enhancement of L-PAM cytotoxicity in the presence of BSO was observed in multidrug-resistant neuroblastoma cell lines, including those that were established at relapse after myeloablative therapy with L-PAM and lines highly resistant to L-PAM due to loss of p53 function, especially at concentrations of L-PAM that were myeloablative

Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses

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