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Taken together, UNC10415667 reveals that slightly larger benzaldehyde-based degraders can effectively recruit FBXO22 via C326 to promote the potent degradation of NSD2 without requiring chemical protection or bioactivation

Interestingly, when these metals are reduced to metallic nanoparticles, they displayed unique and novel properties that were superior to their bulk counterparts

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The work is supported by grants from National Natural Science Foundation of China (32371266 to J.-X.W.) and the non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (no