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Heinrikson, R

Mechanistically, several studies indicated that renal osteopontin, CD44, and TLR4/MyD88/NF-B signaling were involved in the renal damage of HUA (192, 193)

doi: 10.1186/s12906-020-03047-7 155

Moreover, while rheumatoid arthritis patients experience joint stiffness and pain in the early morning, osteoarthritic patients experience pain towards the afternoon

Our conclusions regarding ASCT2-specific causality should be viewed as pharmacological observations that warrant further validation using genetic approaches for gene silencing, such as siRNA- or CRISPR-based methods to definitively confirm the specificity of these findings