Since they can fight free radicals, antioxidants have a substantial impact on human health by potentially delaying the aging process
The conserved motifs and gene structure of CsGSTs were analyzed using MEME and GSDS 2.0 online tools, respectively
doi: 10.1038/s41590-020-0598-4 20 BartelTBHaesslerJBrownTLShaughnessyJDJrvan RheeFAnaissieEet al
Disclosures: Ashish Bibireddy: Nothing to Disclose, Smruti Rath: Nothing to Disclose, Ishaan Dharia: Nothing to Disclose, Gene Im: KorroBio: Consultant, Echosens: Device support for research 1160 LONG-TERM VASCULAR OUTCOMES AND MORTALITY AFTER BARIATRIC SURGERY AMONG PATIENTS WITH OBESITY, TYPE 2 DIABETES, AND METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE Arunkumar Krishnan 1 Diptasree Mukherjee 2 Carolin Schneider 3 Tinsay Woreta 4 Saleh Alqahtani 5 , 1 Atrium Health Levine Cancer, 2 Apex Institute of Medical Sciences, Kolkata, WB, India, 3 RWTH Aachen University, Aachen, Germany, 4 Johns Hopkins University School of Medicine, 5 Johns Hopkins University Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes (T2D) frequently coexist and synergistically increase the risk of adverse clinical outcomes
Specifically, YTHDF1 KO resulted in a reduction of both mRNA and protein levels of Glutathione S-Transferase Mu 2 (GSTM2), a phase II metabolizing enzyme responsible for conjugating glutathione to electrophilic compounds
