b12 injections and type 2 diabetes with metformin and mounjaro? Metformin can cause vitamin B12

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

Dosing typically starts at 0.6 mg and titrates up to 3 mg over several weeks

Common Causes of B12 Deficiency Vitamin B12 deficiency can happen for many reasons

The B12 decline from 567 to 494 mcg/dL represented a 13% drop in 12 months

How long does it take for it to work