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Endogenous reprogramming of alpha cells into beta cells, induced by viral gene therapy, reverses autoimmune diabetes

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SsTyrA and OiTyrA were chosen as they are located at key phylogenetic boundaries within clade I and contain residues required for cofactor binding and catalysis (Figure S2, Data S2)

Moreover, a dull needle may not penetrate the skin and tissue as effectively, leading to improper delivery of medication

The sections were incubated with primary antibodies at a suitable concentration at 4 C overnight