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Glass DJ (2003) Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

1 Background Autoimmune thyroiditis (AITD) is a T-cell-mediated, organ-specific autoimmune disease that mainly manifests as Hashimotos thyroiditis (HT) and Graves disease (GD) (Antonelli et al., 2015)

Despite Dihexas structural derivation from Ang IV, mechanistic studies have established that the compound does not act through the classical AT 4 receptor (insulin-regulated aminopeptidase, IRAP)