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The anti-tissue factor antibody, as well as deficiencies of factors VII, IX and XII affected the thrombin generation potential of malignant cells to different degrees, allowing differentiation of the two different pathways of blood clotting activation by tissue factor or contact activation

Recognizing non-response allows pivoting to alternative approaches rather than continuing ineffective treatment

Mice fogging with vancomycin reduced the number of regulatory T cells while increasing the activity of T cells and NK cells, significantly decreasing tumor metastasis