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We also confirmed that a 6-h treatment with PDD did not significantly affect the expression levels of ubiquitin ligases or proteasome components, or the BRD4 levels, in RNA-Seq analysis (Fig

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In diabetic patients, impaired insulin secretion or insulin resistance disrupts metabolism and cell signal transduction (Sacks et al., 2023

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Br J Nutr 114(8):12461255

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Erastin was shown to induce ferroptosis in lung cancer A549 cells, accompanied by increased oxidative stress, lipid peroxidation, and decreased expression of E-cadherin and SLC7A11

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