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A lack of sufficient vitamin B12 can lead to a range of health issues, from persistent fatigue to more severe neurological changes if left untreated

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Two years later its confirmatory trial failed, and Amylyx pulled it from the market.In both cases, the agency changed its answer once enough pressure came from a drug company facing a deadline, or a patient group with a microphone.Drug company user fees have funded a large share of the FDA's drug review budget since 1992

Staying well-hydrated by drinking plenty of fluids can help mitigate some side effects, such as constipation and kidney strain

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