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These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

These are the leaks in the boat that standard medicine rarely talks about: Energy factory breakdown (mitochondria): Your kidneys run on tiny power plants inside cells

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Ten days after transplantation, the animals were anesthetized with sevoflurane (Maruishi Pharmaceutical), and their livers were removed, embedded in super-cryoembedding medium and frozen quickly in liquid nitrogen

Safety studies For in vitro studies, the cytotoxicity of the agents was assessed using the CCK-8 assay and calcein-AM/propidium iodide (PI) staining