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Experimental elevation of Brk conferred resistance of breast cancer cells to cetuximab (an EGFR-blocking antibody)-induced inhibition of cell signaling and proliferation, whereas knockdown of Brk sensitized the cells to cetuximab by inducing apoptosis

10.1111/j.1365-2605.2008.00951.x 244

After RNA passed the quality control, sequencing libraries were prepared using TruSeq Stranded mRNA Library Prep Kit (Illumina) and IDT Unique Dual Indexes for Illumina (Integrated DNA Technologies) and sequenced using NovaSeq 6000 sequencing system (paired-end mode, read length 100 bp, S4 flow cell