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Description

These modifications reduce its affinity for insulin-like growth factor binding proteins, particularly IGFBP-3, which normally sequesters a large majority of circulating native IGF-1

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Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells

Their preclinical evaluation revealed enhanced receptor-specific uptake and tumor regression, further supporting the viability of targeted liposomal delivery platforms in precision oncology [123]