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20 In 2017, Paul and Brady came to similar conclusions that all four forms appear to be effective, although they point out research that shows that tissue retention of cyano-B12 is lower and urinary excretion higher than that of the other forms, although this statement is based on a review from 1965

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Therapists should follow these hEDS exercises guidelines: Prioritize single-joint exercises over compound exercises Use light weights and higher repetitions Emphasize good form and control Avoid joint hyperextension Include rotator cuff exercises Include stability exercises for knees and ankles Use gentle stretching exercises with limited range of motion Before beginning physical therapy exercises, certain issues may need to be addressed, including hEDS joint pain, load transfer failures, fascia restrictions, tendinopathies and nerve entrapment