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In short, when sound waves travel through the cochlea, they trigger the movement of cilia on the surface of the hair cell, triggering the opening of the MET channel, which then encourages the depolarizing influx of ions into hair cells and the generation of electrical signals

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Recent structural and mechanistic advancesmost notably the catalytic cysteine trisulfideclarify how membrane context and substrate availability tune catalytic flux, yet debate persists over the physiological sulfur acceptor (glutathione versus sulfite) and how microenvironments route sulfide

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This can help reduce the risk of chronic diseases and problems related to aging