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Cell Biophys 1983;5:12940

Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees

TRPV1 (Transient Receptor Potential channels) and TRPA1 ion channels on sensory nerve endings are upregulated, meaning that chemical stimuli that would be imperceptible on healthy skin trigger pain signaling and neurogenic inflammation in rosacea skin

This unique property makes it the master antioxidant and a critical component in the bodys defense system against oxidative stress

Abnormally high concentrations of Cu have been found in the striatum in patients with HD and in mouse models of HD