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Magnoflorine inhibited p65 and IkB, which in turn inhibited the activation of NF-B and the phosphatidylinositide 3-kinase (PI3K)/protein kinase B (Akt) pathway, exerting anti-inflammatory effects and inhibiting the release of IL-6, IL-8, iNOS and COX-2 to subsequently reduce the inflammatory response

doi: 10.1007/s11926-012-0272-4 204 ZhengXYuXWangCLiuYJiaMLeiFet al

Vitamin E can be regenerated from its -tocopheroxyl radical form (-TO ) to -tocopherol (Jomova et al

doi: 10.18632/oncotarget.21601 43 DeBerardinisRJChengT

However, whether CXCR5 can be a viable target requires further development of inhibitors and exploration in animal models and clinical trials