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Description

Nature 501 , 5257 (2013)

Azhar M

Moreover, the serum level of IL-6 in lipopolysaccharide(LPS)-stimulated mice was significantly elevated compared to normal controls, further supporting the accuracy and effectiveness of this delivery strategy

Limitations of This Comparison Several structural limitations constrain everything above, and honest readers should keep them in view: Species and model gap

Collectively, engineered bacteria enhance immunotherapy by targeting three core metabolite-mediated processes in the TME: (1) producing immunostimulatory metabolites (c-di-AMP, L-Arg, butyrate) to activate effector immune cells