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This forces the body to utilize the secondary eliminative organs: lungs, sinuses, skin, and more

3.1 Targeted GSH depletion in mitochondria for enhanced PDT efficacy Mitochondria-often referred to as the cells energy powerhouse-are particularly vulnerable to oxidative stress (Zhu et al., 2022)

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Consequently, ser/gly metabolism has been linked to tumor pathogenesis, poor outcome, and resistance to chemotherapy and targeted therapies in NSCLC [5, 16, 17]