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Functionalized PLGA nanoparticles, modified with ligands or peptides, demonstrated the ability to cross the BBB, enabling their use in neurological disorders like PD 116,117

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once) to the mice causes significant liver damage and necrosis of cells as evidenced by the elevated serum hepatic enzymes alanine aminotransferase (ALT), aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GT) compared with normal group [3]