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Although the potential of AFPs has been recognized, the precise mechanisms underlying the antifungal activity of AFPs remain incompletely understood

13), precluding reliable immunolabeling of GSDMD-N fragments in HCs or SCs

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These interactions stabilize the inactive conformation of GSK3, preventing its hyperactivity, which is associated with tau hyperphosphorylation and neurofibrillary tangle formation (Figure 5ah)