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We induced the expression of 196 distinct phage AGs in a pooled format, in each strain represented in the 45 phage-host combinations to identify genes that enhanced phage reproduction (Supplementary Data 1)

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Interactions with other receptors also occur, including ligand-gated ion channels, as well as GPCRs leading to homo- and heterodimer formation

These findings constitute a proof of concept that pramlintide may have therapeutic use as an anti-obesity agent