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2021 Jul;7(4):877-885

Surgeries to remove parts (or all) of the stomach or small intestine

The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

People with Unexplained Fatigue or Cognitive Decline: Chronic fatigue, brain fog, and memory issues are all signs of possible B12 deficiency or impaired methylation