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doi:10.1370/afm.1517

GLUTATHIONE & MALE INFERTILITY Remember, it is well understood that oxidative stress (inflammation) interferes with normal sperm function via membrane lipid peroxidation (cell membrane fatty acid damage) and fragmentation or damage of nucleic acids (DNA)

Kerns, C

These results suggested that in addition to its role in TDMD, ZSWIM8 might act more broadly to destabilize AGOmiRNA complexes that contain extensively trimmed miRNAs

Unsurprisingly, enzymes containing FeS clusters are particularly susceptible to iron deficiency and oxidative stress [76,77], as the instability and gradual degradation of these clusters can cause irreversible damage to the enzyme's protein backbone [78]