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Once the tyrosinase process has been inhibited the metabolic pathway then turn its course going to the synthesis of light pigmented melanin called Phaeomelanin instead of synthesizing dark pigmented melanin called Eumelanin

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Intestinal glandular epithelial cells in Crohns disease and ulcerative colitis express abundant PLA2G2A, whereas inflammatory cells lack this protein

The answer is nuanced and depends entirely on the goals of the study