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Second, in latently infected macrophages the metabolic steps in the tricarboxylic acid (TCA) cycle preceding oxidative phosphorylation (OXPHOS) were compromised, resulting in lipid accumulation, which is typically observed in several tissues and cells in the HIV infected population 18,19

LncRNAs are involved in regulating ageing and age-related disease through the adenosine monophosphate-activated protein kinase signalling pathway

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In conclusion, the evidence suggests that IST-induced covalent oligomerization of p62 to activate Nrf2 may represent a promising avenue for the treatment of RA [132]

J Biol Chem 276:70117016 Springael J, Penninckx MJ (2003) Nitrogen-source regulation of yeast -glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3