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6 CUS is highly accurate for diagnosing the more dangerous DVTs affecting proximal veins, but is less accurate in identifying distal DVTs

When to Suspect APD APD should be suspected when: Skin symptoms recur monthly despite standard dermatologic treatment Symptoms reliably worsen before menstruation Reactions appear after starting progesterone or progestins Antihistamines provide partial but not complete relief Related: Histamine Intolerance: What It Is & What to Do About It APD Causes and Risk Factors APD develops due to an autoimmune response to progesterone, though the exact mechanism of this hypersensitivity is not fully understood

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If you are consistently more tired than before starting ipamorelin after the first two weeks, your protocol needs adjustment

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