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Someone managing chronic stress requires more B vitamins and magnesium than someone with low stress

Longevity 2016 (2016) 118

However, the effect was not significant enough to be considered a miracle solution

Cardiovascular effects are characterized and mild: a transient systolic blood pressure increase of approximately 6 mmHg peaking at 2 to 4 hours post-dose, with a heart rate reduction of up to 5 beats per minute