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After dislodging, rosettes were incubated in wells coated with 0.2% porcine gelatin to allow the non-neural cells to differentially attach 21

Treatment: Lipoic Acid IV Therapy coupled with Hyperbaric Oxygen was commenced along with an oral metabolic protocol

Tumbling of cells in vivo was associated with a greater value in the same study

Thus, while BDNF provides a reference for studying neurotrophic signaling in PD, its translational potential is constrained by inherent biological characteristics and the lack of clinical validation