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10.1038/9045 117 WangH.RaoB.LouJ.LiJ.LiuZ.LiA.et al (2020)

By contrast, several mutations that decrease the tone of the GH/IGF-1 axis are associated with extended longevity in mice

Women are more commonly affected than men and it tends to run in families

Blood was flushed out with 150 mL of saline with 100 U/L heparin at 30 mL/min, followed by perfusion with 3% formaldehyde and 150 mL of 1% glutaraldehyde solution