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Therefore, p53 is widely regarded as undruggable

Ufuk F, Herek D

PMID: 41866332 Am J Physiol Renal Physiol Anatomic and functional evidence for renal autonomic innervation in normotensive and hypertensive rats

Cycloheximide (CHX) degradation assay To exclude the translational effect, HCT116 were treated with a protein biosynthesis inhibitor CHX (50 g/mL, Sigma), so that the only changes would be attributed to the already translated proteins