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10.1016/j.bcp.2019.113684 52 LiuX

The Amsterdam II criteria serve as a guideline for identifying families at high risk for LS, an autosomal dominant disorder that increases susceptibility to cancer

For instance, artificial mitochondrial transplantation (AMT/T) technology combined with nanocarriers addresses challenges such as mitochondrial heterogeneity and poor in vivo operability [158, 159]

EAAC1 deleted mice exhibit age-dependent loss of dopaminergic neurons in the substantia nigra and heightened oxidative stress

This constant state of high alert places immense strain on the HPA axis, eventually leading to a blunted or dysregulated cortisol response