Its particles can be incorporated into dental materials, releasing Zn + (combats oral bacteria and reduces dentin demineralization), F (inhibits demineralization), and Ca 2+ (enhances remineralization) ions to prevent secondary caries ( 2+ /Ca 2+ ( In vitro salivary titration assembly revealed that BioUnion-incorporated GIC provides higher initial fluoride release and a more sustained release profile under simulated oral conditions ( 2.1.2 Eugenol Whereas BioUnios strategy relies on antibacterial action and remineralization, eugenol acts primarily through pathogen inhibition and pulp inflammation modulation to prevent secondary caries ( These systems retain Eugenols functionality while achieving slow, sustained drug release, and can be triggered to release in response to specific environmental stimuli, thereby avoiding the cytotoxicity associated with long-term high-concentration release, improving biosafety ( 2+ , which achieves pH-responsive release via a phenolic hydroxyl-Zn 2+ cage-like network where the released Eugenol generates reactive oxygen species (ROS) to disrupt biofilms ( + ) and Gram-negative(G - ) bacteria while avoiding detrimental effects on resin polymerization and strength ( 2.1.3 Tannic acid Nanotechnology not only overcomes the limitations of natural active substances but also endows them with new functionalities
In Amino acid metabolism pathway, the MCE+LPS group significantly increased the levels of L-aspartic acid, L-glutamate, L-serine, -alanine, and 5-Hydroxy-L-tryptophan compared with the LPS group
doi: 10.3389/fcell.2025.1685252 Received 13 August 2025 Accepted 08 October 2025 Published 23 October 2025 Volume 13 - 2025 Edited by Hilary Ann Coller, University of California, Los Angeles, United States Reviewed by Jianyun Liu, Indiana University Bloomington, Bloomington, United States Ruoxi Zhang, University of Texas Southwestern Medical Center, United States Updates Copyright 2025 Peng, Zhang, Ma, Zhang, Guan and Yu
Setria Glutathione is superior to other glutathione in the fact that it is manufactured through a patented, fermentation process that contains no additives, artificial flavours and preservatives
Glutathione is the master antioxidanta protein that occurs naturally in every cell in your body
