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Innovative extracellular domain designs, such as TSHR-CAR-T cells, have emerged (80)

While these results are broadly in line with the previously reported role of activated KRAS in supporting de novo serine synthesis 17 , it is clear that other genetic alterations such as amplification of PHGDH in MDA-MB-468 cells 14 also contribute to the dependence of cancer cells on a supply of exogenous serine

Glutathione is not inherently dangerous

ROC curve analysis revealed that our multivariable prognostic model achieved good predictive performance in the TCGA-LUAD training set, with 1-, 3-, and 5-year AUC values of 0.716, 0.711, and 0.685, respectively ( Figure 12A )