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Withdrawal of Approval of 92 New Drug Applications and 49 Abbreviated New Drug Applications (2009)

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In anemia related to vitamin B12 deficiency, an appropriate B12-containing regimensometimes alongside iron or folate when indicatedhelps restore hematologic parameters and reduce neurologic symptoms when instituted promptly and correctly

And where its most relevant to our discussion is how the presence of these mutations impacts how well your body can or cant use certain formulations of B12