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For the qualitative phase, purposive sampling targeted individuals who scored in the severe or extreme ranges on the Depression Anxiety Stress Scale-21 (DASS-21)

Local corticosteroids, calcineurin inhibitors and phototherapy are still the basis of treatment, and long-term use of steroids can lead to decreased immunity (Whitton et al., 2016)

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Therefore, in these types of cancer vitamin K may be contraindicated

Anchoring this point firmly matters, because it is the factual backbone of the entire injectable-versus-topical comparison: the route with human cosmetic data is the one you apply, not the one you inject