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This process is known as genomic or nuclear response and entails up- and down-regulation of diverse genes associated with cell proliferation, survival, and migration (Musgrove and Sutherland, 2009

In men, it aids sperm production

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Considering that current cancer diagnoses primarily rely on features observed in cancer cells at primary sites, gaining a deeper understanding of the lipidomic and metabolic adaptations that occur during LN metastasis could offer novel solutions to prevent the spread of cancer cells