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The biodegradability of NP4 upon internalization into the cancer cells was studied upon encapsulation of the dye Nile Red into a nanoparticle formulation, followingly referred to as NP4-NR

Subjects were randomly split 80:20 to derivation (n=2292) and validation (n=573) cohorts

The study utilized two abdominal computed tomography (CT) scans, conducted at baseline and at a 1-2-year follow-up, to measure liver volume and chest width, respectively, in order to calculate standard liver volume (ELV) and the rate of change of liver volume ratio (LV/ELV%) over the course of 1 to 2 years

Severe intestinal epithelial damage is also considered to be the main cause of death from HS [12]

doi: 10.3390/ijms231810217, 14