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Abbreviations CVD: Cardiovascular disease HF: Heart failure HFrEF: Heart failure with reduced ejection fraction IV: Intravenous ID: Iron deficiency TSAT: Transferrin saturation FCM: Ferric carboxymaltose DCYTB: Duodenal cytochrome B CRT: Cardiac resynchronization therapy CMR: Cardiac magnetic resonance ROS: Reactive oxygen species ATP: Adenosine triphosphate Fe: Iron FPN: Ferroportin sTfR: Soluble transferrin receptor TIBC: Total iron-binding capacity HIF: Hypoxia-inducible factor IL: Interleukin eNOS: Endothelial nitric oxide synthase HFE: Hemochromatosis gene AHA: American Heart Association ACC: American College of Cardiology HFSA: Heart Failure Society of America ESKD: End-stage kidney disease References WHO

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Proprietary blend 280 mg* of: Rosemary (Rosemarinus officinalis)(leaf), N-Acetyl Cysteine, Milk Thistle (seed), Superoxide Dismutase (bovine), Catalase, L-Glutamine, Alpha Lipoic Acid, Milk Thistle Extract (Silybum marianum)(seed), Turmeric (curcumin)(rhizome) Extract, Glutathione (reduced)

If the gel is prescribed for facial use, apply it as directed, avoiding sensitive areas like the eyes and mouth

Miyoshi, A., Rochat, T., Gratadoux, J.J., Le Loir, Y., Oliveira, S.C., Langella, P., and Azevedo, V., Oxidative stress in Lactococcus lactis, Genet