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Abu-Sbeih, H, Szafron, D, Elkafrawy, AA, Garcia-Rodriguez, V, Ma, W, Xu, A, Khurana, S, Numan, L, Chen, E, Goldstein, R, Tsen, A, Peng, Y, Blum Murphy, M, Kopetz, S , Ikoma, N, Shatila, M, Qiao, W, Raju, GS, Ross, WA, Ge, PS, Coronel, E, Wang, Y

The moiety -L-D of formula (VIII) can be prepared following procedures that are known in the art of organic synthesis (chemical reactions, extraction, evaporation, precipitation, chromatography, filtration, trituration, crystallization, and the like), and analytical procedures, which are known to persons of ordinary skill in the art of analytical chemistry