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Although reactive electrophiles such as chloroacetamides are generally considered to be promiscuous in target binding, we demonstrated here using a BODIPY-labelled analogue that the chloroacetamide-based GSTO1 inhibitor C1-27 exhibited a low degree of nonspecific reactivity

Crit Rev Biochem Mol Biol 57:333350 Huang D, Kraus WL (2022) The expanding universe of PARP1-mediated molecular and therapeutic mechanisms

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Given that M-cells have well-accepted BT capability and overlie intestinal lymphoid aggregates, M-cell mediated BT is one plausible mechanistic explanation [16, 17]

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