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Description

The question is how quickly, at what cost, and with what safety profile

PubMed: (peer-reviewed) Simon A, et al

This is the most important safety variable and the one most often overlooked

BMC Pediatr 20 , 381 (2020)

Topline results announced in December 2025 were positive, showing that patients who switched from injectables to oral orforglipron maintained their weight loss