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Twenty-six subjects were entered into the study and none showed an adverse reaction to the single intradermal injection

Application frequency for topical protocols is typically once or twice daily, applied to cleansed skin at the target area

Using ChatGPT to independently assess treatment photos (and finding it aligned within 7.5% of dermatologists) demonstrates a scalable approach for future studies

Gene expression shifts from tissue destruction to repair patterns with 127 genes altered, upregulating repair genes while downregulating inflammatory genes

The peptide also increases integrin expression in basal keratinocytes at concentrations of 0.1-10 micromolar, enhancing p63 positivity, a transcription factor that maintains stem cell characteristics