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Clinical studies have shown that at the time of diagnosis, -cell mass and function are significantly reduced in patients with T2DM [27]

Braz J Microbiol 53 , 3350 (2022)

Next, an acidic amino acid residue donates a proton back to C-3, but from the opposite face, resulting in inversion at C-3 and formation of xylulose 5-phosphate