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Because the neural tube closes in the first four weeks of gestation, often before many women even know they are pregnant, many countries in time decided to implement mandatory food fortification programs

This feature makes polymeric nanoparticle vaccines particularly attractive for cancer immunotherapy, as they can deliver antigens to tumor or inflamed tissues [113]

In these cases, the perforations leak pus and stool out of the colon into the abdominal cavity, a condition called peritonitis

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Notably, PEGylation prevented immune complex formation and anti-uricase antibody induction in avian models, underscoring its translational potential