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56 HongL.MengX.LiC.SangS.PattenC.ShengS.et al (2003)

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doi: 10.1016/j.molcel.2017.06.017 53 HuangWGongYYanL

La mise en vidence de l'effet de synergie exerc par la L-lysine (et ses sels) vis--vis des effets biologiques de la L-carnitine en combinaison quimolaire a t ralise avec un modle exprimental chez le Rat Wistar bas sur l'tude des fonctions musculaires (excitabilit, contractilit) perturbes par un jene de 5 jours.The demonstration of the synergistic effect exerted by L-lysine (and its salts) vis--vis the biological effects of L-carnitine in equimolar combination was carried out with an experimental model in the Rat Wistar based on the study of muscle functions (excitability, contractility) disturbed by a 5-day fast

However, it was found to selectively induce apoptosis in human lymphoma cells, Daudi, Raji and Jurkat cells, by depleting the intracellular glutathione level rather than increase it